Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. In July 2021, the Government of. Analytical cookies are used to understand how visitors interact with the website. GENEVA, SWITZERLAND / ACCESSWIRE / November 8, 2022 / RELIEF THERAPEUTICS Holding SA (SIX:RLF)(OTCQB:RLFTF)(OTCQB:RLFTD) ("Relief"), today announced that they and NRx Pharmaceuticals, Inc. ("NRx") have further extended the stay of their pending litigation until November 11, 2022.While the parties are very far along in their negotiation of settlement documents, no final agreements have been . 53 LRThe issuer is solely responsible for the content of this announcement.RELIEF THERAPEUTICS HOLDING SA AND NRX PHARMACEUTICALS, INC. FURTHER EXTEND THEIR STAY OF PENDING LITIGATION TO PROVIDE ADDITIONAL TIME FOR THE PARTIES TO FINALIZE THEIR LITIGATION . People facing life-threatening diseases need the possibility of tomorrow. It works only in coordination with the primary cookie. These changes are generally and notably different then the mood changes most experience. This cookie contains random number which is generated when a visitor visits the website for the first time. The cookie is used to store the user consent for the cookies in the category "Other. GENEVA, SWITZERLAND / ACCESSWIRE / November 8, 2022 / RELIEF THERAPEUTICS Holding SA (SIX:RLF)(OTCQB:RLFTF)(OTCQB:RLFTD) ("Relief"), today announced that they and NRx Pharmaceuticals, Inc. ("NRx") have further extended the stay of their pending litigation until November 11, 2022.While the parties are very far along in their negotiation of settlement documents, no final agreements have been . Severe Bipolar Depression in patients with Acute Suicidal Ideation & Behavior (ASIB), Research Site, Birmingham, Birmingham, Alabama, United States | Research Site, Charlotte, Charlotte, North Carolina, United States | Research Site, Houston, Houston, Texas, United States, Bipolar Depression in patients with Sub-Acute Suicidal Ideation & Behavior (SSIB), JP Smith Hospital, Fort Worth, Texas, United States | Research Centers of America, Hollywood, Florida, United States | Research Site, Birmingham, Birmingham, Alabama, United States | Research Site, Houston, Houston, Texas, United States | Texas Health Hospital Frisco, Frisco, Texas, United States | University of California Irvine, Irvine, California, United States | University of Louisville Hospital, Louisville, Kentucky, United States | University of Utah Health (Site 211-002), 419 Wakara Way, Ste. The cookie is used to store the user consent for the cookies in the category "Other. We also use third-party cookies that help us analyze and understand how you use this website. YouTube sets this cookie to store the video preferences of the user using embedded YouTube video. It works only in coordination with the primary cookie. The contents of this site are intended for US Healthcare Professionals. Cancel. This cookie is set by GDPR Cookie Consent plugin. Analytical cookies are used to understand how visitors interact with the website. YSC cookie is set by Youtube and is used to track the views of embedded videos on Youtube pages. Relief Therapeutics Holding SA and NRx Pharmaceuticals, inc. . These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc. NRX-101 is a patented, oral fixed-dose combination of two FDA-approved drugs: D-cycloserine, an NMDA receptor modulator; and Lurasidone, a 5-HT2a receptor antagonist. This cookie is used for websites which is having multiple domains to identify the same visitor across multiple domains. The cookie is used to store the user consent for the cookies in the category "Analytics". Currently, the only FDA approved treatment for patients with Bipolar Depression and Acute Suicidal Ideation and Behavior (ASIB) is electroshock therapy, a procedure, done under general anesthesia, in which electric currents are passed through the brain, intentionally triggering a brief seizure. RADNOR, Pa., Nov. 16, 2021 (GLOBE NEWSWIRE) -- NRx Pharmaceuticals (Nasdaq: NRXP) (NRx), a clinical-stage, biopharmaceutical company, today provided a business update and financial results for the . It does not store any personal data. This is a session cookie set during the first display of the page on each visit. Locations Primary 1201 N Market Street Suite 111 Wilmington, Delaware 19801, US Get directions Employees at NRx Pharmaceuticals, Inc. Dr. Dennis K. McBride Drew Evans Director of Digital. MediaMath sets this cookie to avoid the same ads from being shown repeatedly and for relevant advertising. The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. Not an offer or recommendation by Stocktwits. These cookies ensure basic functionalities and security features of the website, anonymously. These cookies will be stored in your browser only with your consent. The Noteholder has the right to redeem up to $1,000,000 of the outstanding balance of the Note per month starting 6 months after the issuance date. This cookie is used for setting an unique ID for the visitor which helps to get the accurate number of specific visitor on the website. This wasn't going to be enough cash to fund the entire pipeline and so it chose to. Our website uses cookies to improve your experience while you navigate through the website. Other uncategorized cookies are those that are being analyzed and have not been classified into a category as yet. Financial Results for the Year Ended December 31, 2021. The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. The company reported in July that Zyesami statistically significantly prevented a steep surge in cytokines or cytokine storm in Covid-19 patients in a Phase IIb/III trial. Relief is a Swiss, commercial-stage, biopharmaceutical company focused on identification, development and commercialization of novel, patent protected products intended for the treatment of rare . The companys lead program NRX-101, an oral, fixed-dose combination of D-cycloserine and lurasidone, targets the brains NMDA receptor and is being investigated in a Phase 3 trial under an FDA Special Protocol Agreement and Breakthrough Therapy Designation in patients with bipolar depression and suicidal ideation, an indication for which the only approved treatment is electroshock therapy. The cookie is used to store the user consent for the cookies in the category "Other. Performance cookies are used to understand and analyze the key performance indexes of the website which helps in delivering a better user experience for the visitors. You also have the option to opt-out of these cookies. This is a session cookie set during the first display of the page on each visit. For people living with unmet medical needs. "I am honored to have been chosen by the NRx Pharmaceuticals Board to lead the Company as it conducts its trials for NRX-101 in the treatment of Suicidal Bipolar Depression and continues to develop its pipeline of drugs for depression, PTSD, and other potential neuroscience indications based on more than 90 issued and pending patents worldwide," said Willard. This cookie contains random number which is generated when a visitor visits the website for the first time. But opting out of some of these cookies may affect your browsing experience. View our. Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features. The cookie is used to allows the paid version of the plugin to connect entries by the same user and is used for some additional features like the Form Abandonment addon. 8, 2022, 10:25 PM. This cookie contains random number which is generated when a visitor visits the website for the first time. A cookie set by YouTube to measure bandwidth that determines whether the user gets the new or old player interface. These cookies track visitors across websites and collect information to provide customized ads. NRx Research Pipeline Our pipeline includes the first drug in development to treat Bipolar Depression in Patients with Acute and Sub-Acute Suicidal Ideation & Behavior (ASIB & SSIB). This cookie contains random number which is generated when a visitor visits the website for the first time. The cookie is used to allows the paid version of the plugin to connect entries by the same user and is used for some additional features like the Form Abandonment addon. The Companys right to satisfy the redemption amount in common stock is subject to certain conditions. GENEVA, SWITZERLAND / ACCESSWIRE / November 8, 2022 / RELIEF THERAPEUTICS Holding SA (SIX:RLF)(OTCQB:RLFTF)(OTCQB:RLFTD) ("Relief "), today announced that they and NRx Pharmaceuticals, Inc. ("NRx") have further extended the stay of their pending litigation until November 11, 2022.While the parties are very far along in their negotiation of settlement documents, no final agreements have been . Bipolar disorder is an illness that causes notable changes in a persons mood, energy and at times his or her ability to think clearly. The cookies is used to store the user consent for the cookies in the category "Necessary". The cookies is used to store the user consent for the cookies in the category "Necessary". Someone attempts suicide every 27 seconds in the United States and the only approved treatment of suicidal bipolar depression remains electroshock therapy. View our. Our website uses cookies to ensure best user experience. Records the default button state of the corresponding category & the status of CCPA. This cookie is used to shoot certain codes on the first display of the page and also to enhance the speed of the website. 02 June 2021. . The cookie is used to store the user consent for the cookies in the category "Performance". suzanne.messere@sternir.com. This cookie is used for counting the new visitors to the website by assigning a unique visitor ID. Our website uses cookies to ensure best user experience. Advertisement cookies are used to provide visitors with relevant ads and marketing campaigns. The cookie is used to store the user consent for the cookies in the category "Performance". These cookies will be stored in your browser only with your consent. Other uncategorized cookies are those that are being analyzed and have not been classified into a category as yet. This cookie is set by GDPR Cookie Consent plugin. YSC cookie is set by Youtube and is used to track the views of embedded videos on Youtube pages. Expanded Access Policy on RTT: Aviptadil needs to be requested by a physician. This cookie is used by the WPForms WordPress plugin. Announce Tentative Settlement Of Pending Litigation, NRx Pharmaceuticals Provides Business Update and Reports Second Quarter 2022 Results Focusing on Reactivation & Advancement of its Psychiatry Franchise. You also have the option to opt-out of these cookies. These cookies ensure basic functionalities and security features of the website, anonymously. RELIEF THERAPEUTICS HOLDING SA AND NRX PHARMACEUTICALS, INC. FURTHER EXTEND THEIR STAY OF PENDING LITIGATION TO PROVIDE ADDITIONAL TIME FOR THE PARTIES TO FINALIZE THEIR LITIGATION SETTLEMENT. Geneva, . The contents of this site are intended for US Healthcare Professionals. SiteLock sets this cookie to provide cloud-based website security services. This cookie is set by GDPR Cookie Consent plugin. Necessary cookies are absolutely essential for the website to function properly. Relief Therapeutics Holding SA and NRx Pharmaceuticals, inc. further extend their stay of pending litigation to provide additional time for the parties to finalize their litigation settlement 08 . RELIEF THERAPEUTICS Holding SA is listed on the SIX Swiss Exchange under the symbol RLF and quoted in the U.S. on OTCQB under the symbols RLFTF and RLFTY. The cookie is used to store the user consent for the cookies in the category "Other. Source: MediaMath sets this cookie to avoid the same ads from being shown repeatedly and for relevant advertising. A load balancing cookie set to ensure requests by a client are sent to the same origin server. NRx's product pipeline includes Zyesami, . The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. This cookie is set by GDPR Cookie Consent plugin. It works only in coordination with the primary cookie. We also use third-party cookies that help us analyze and understand how you use this website. Records the default button state of the corresponding category & the status of CCPA. This cookie, set by Cloudflare, is used to support Cloudflare Bot Management. The Company assumes no obligation to revise any forward-looking statement, whether as a result of new information, future events or otherwise. Sign Up. The cookie is used to store the user consent for the cookies in the category "Performance". This cookie is used by the WPForms WordPress plugin. These cookies ensure basic functionalities and security features of the website, anonymously. The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". This cookie is used to identify the new visitors to the website. NRx Pharmaceuticals Produces First Phase 3-stage NRX-101 Drug Made Using Commercial Process, Relief Therapeutics Holding SA And NRx Pharmaceuticals, Inc. Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features. MediaMath sets this cookie to avoid the same ads from being shown repeatedly and for relevant advertising. Its products include ZYESAMI . The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc. Please certify that you are a healthcare professional by clicking the appropriate link below. This cookie is set by GDPR Cookie Consent plugin. This cookie contains random number which is generated when a visitor visits the website for the first time. YouTube sets this cookie to store the video preferences of the user using embedded YouTube video. View our. Relief's diversified pipeline consists of assets that have the potential to effectively address significant unmet medical needs, . This cookie is set by Rubicon Project to control synchronization of user identification and exchange of user data between various ad services. The cookie is used to store the user consent for the cookies in the category "Other. Analytical cookies are used to understand how visitors interact with the website. Ocugen Provides Business Update & Third Quarter 2022 Financial Results. Pallaskorpi, et al. These changes are generally and notably different then the mood changes most experience. Bipolar depression (lows) is a common symptom of this mental illness. In July 2021, the Government of Israel awarded NRx the exclusive worldwide right to develop and market the BriLife COVID vaccine developed by the Israel Institute for Biological Research. This cookie is used to identify the new visitors to the website. The cookies is used to store the user consent for the cookies in the category "Necessary". YouTube sets this cookie via embedded youtube-videos and registers anonymous statistical data. Performance cookies are used to understand and analyze the key performance indexes of the website which helps in delivering a better user experience for the visitors. The Company intends to use the net proceeds from the Note (approximately $10 million) to support its NRX-101 development programs for the treatment of suicidal bipolar depression and PTSD and for general corporate purposes. But opting out of some of these cookies may affect your browsing experience. RADNOR, Pa., July 13, 2022 /PRNewswire/ -- NRx Pharmaceuticals, Inc. (Nasdaq: NRXP ): ("NRx Pharmaceuticals", or the "Company"), a clinical-stage biopharmaceutical company, today announced. This cookie is set by GDPR Cookie Consent plugin. YouTube sets this cookie to store the video preferences of the user using embedded YouTube video. A load balancing cookie set to ensure requests by a client are sent to the same origin server. It does not store any personal data. Set by the GDPR Cookie Consent plugin, this cookie is used to record the user consent for the cookies in the "Advertisement" category . Harry B. Peled, M.D. Suicide Attempts and Completions in Patients With Bipolar Disorder, Psychiatric Times, 2007, NRX-101 is an investigational treatment for bipolar depression in patients with Acute and Sub-Acute Suicidal Ideation and Behavior (ASIB, SSIB). The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". NRx Pharmaceuticals, Inc. (Nasdaq: NRXP), a clinical-stage biopharmaceutical company, today announced its Chief Executive Officer, Stephen Willard, and other executive leaders will be presenting. A load balancing cookie set to ensure requests by a client are sent to the same origin server. RELIEF THERAPEUTICS Holding SA and NRx Pharmaceuticals, Inc. extend their stay of pending litigation to provide additional time for the parties to finalize their settlement 26-Oct-2022 / 07:00 CET . This cookie is set by GDPR Cookie Consent plugin. Earlier this month, NRx Pharmaceuticals entered an agreement with MannKind to create a dry powder formulation of Zyesami for the treatment of various respiratory ailments. SiteLock sets this cookie to provide cloud-based website security services. Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features. This cookie is set by GDPR Cookie Consent plugin. Advertisement cookies are used to provide visitors with relevant ads and marketing campaigns. ** Data and rights held by Research Foundation for the State University of New York; NRx Pharmaceuticals has a license. We bring them hope through life-saving medicines. The cookie is used to store the user consent for the cookies in the category "Analytics". A separateinhaledstudy that was being conducted by Quantum Leap Healthcare Collaborative (I-SPY) has been stopped. We accomplish our mission by directing scientific and clinical expertise towards innovative clinical protocols. Today NRx has a pipeline of late-stage drugs that can serve as platform for numerous indications in the psychiatry and respiratory space (e.g., non-COVID-19 ARDS)." Flynn continued, "After. The cookie is used to store the user consent for the cookies in the category "Analytics". Other uncategorized cookies are those that are being analyzed and have not been classified into a category as yet. This is a session cookie set during the first display of the page on each visit. Records the default button state of the corresponding category & the status of CCPA. Bipolar disorder is an illness that causes notable changes in a person's mood, energy and at times his or her ability to think clearly. CORPORATE CONTACT This cookie is used to shoot certain codes on the first display of the page and also to enhance the speed of the website. Our pipeline includes the first drug in development to treat Bipolar Depression in Patients with Acute and Sub-Acute Suicidal Ideation & Behavior (ASIB & SSIB). Set by the GDPR Cookie Consent plugin, this cookie is used to record the user consent for the cookies in the "Advertisement" category . Our website uses cookies to ensure best user experience. But opting out of some of these cookies may affect your browsing experience. The cookies is used to store the user consent for the cookies in the category "Necessary". This cookie, set by Cloudflare, is used to support Cloudflare Bot Management. This cookie is used to shoot certain codes on the first display of the page and also to enhance the speed of the website. This cookie is set by GDPR Cookie Consent plugin. Payments may be made by the Company at its option in: (i) cash, (ii) shares of our common stock, or (iii) a combination of cash and shares of our common stock. NRx Pharmaceuticals has also initiated a Phase 2b clinical trial in patients with Sub-Acute Suicidality, a substantially broader indication. The cookie is used to store the user consent for the cookies in the category "Analytics". The contents of this site are intended for US Healthcare Professionals. Keep up with the latest news and updates about NRx through social media. This cookie is used for setting an unique ID for the visitor which helps to get the accurate number of specific visitor on the website. NRX Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, develops novel therapeutics for the treatment of central nervous system disorders and life-threatening pulmonary diseases. We also use third-party cookies that help us analyze and understand how you use this website. A load balancing cookie set to ensure requests by a client are sent to the same origin server. OCGN. MediaMath sets this cookie to avoid the same ads from being shown repeatedly and for relevant advertising. These cookies will be stored in your browser only with your consent. Records the default button state of the corresponding category & the status of CCPA. * This study has been paused while NRx evaluates whether to increase the sample size, change the trial endpoint / enrollment criteria or discontinue the study. Please certify that you are a healthcare professional by clicking the appropriate link below. This cookie is used for counting the new visitors to the website by assigning a unique visitor ID. We also use third-party cookies that help us analyze and understand how you use this website. While the parties are very far along in their negotiation of settlement documents, no final agreements have been . NRx brings hope: This cookie is used by the WPForms WordPress plugin. In addition, the Company is commercializing several legacy products via licensing and distribution partners. We leverage proven science and clinical expertise to identify and apply medical solutions as immediately as possible, while simultaneously focusing on expanding therapeutic potential for the future. Private Securities Litigation Reform Act of 1995, which may include, but are not limited to, statements regarding our financial outlook, product development, business prospects, and market and industry trends and conditions, as well as the Companys strategies, plans, objectives, and goals. NASDAQ 0.00%. The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. NRx Pharmaceuticals pipeline includes medicinal candidates in Phase 2, and Phase 3 trials for COVID-19-related Lung Injury and Acute Respiratory Distress (ARDS) in partnership with Relief Therapeutics, AG, and the first drug in development to treat Bipolar Depression in Patients with Acute Suicidality. This cookie is set by GDPR Cookie Consent plugin. Finally, Relief's 2021 acquisitions of APR Applied Pharma Research SA and AdVita Lifescience GmbH brought to Relief a diverse pipeline of marketed and development-stage programs. These cookies track visitors across websites and collect information to provide customized ads. Relief's diversified pipeline consists of assets that have the potential to effectively address significant unmet medical needs, including PKU GOLIKE , engineered with Relief's proprietary . According to the 10-Q SEC Filing, NRx Pharmaceuticals had $38.9 million in cash as of September 30 2021. The Note has an interest rate of 9% per annum and has a maturity date of 18 months. mcogan@nrxpharma.com, INVESTOR RELATIONS You also have the option to opt-out of these cookies. This cookie is used for setting an unique ID for the visitor which helps to get the accurate number of specific visitor on the website. SiteLock sets this cookie to provide cloud-based website security services. Discovery Pipeline We are NRx - an agile and specialized biopharma company, resolutely focused on meeting very high unmet medical needs. Analytical cookies are used to understand how visitors interact with the website. Finally, Relief's 2021 acquisitions of APR Applied Pharma Research SA and AdVita Lifescience GmbH brought to Relief a diverse pipeline of marketed and development-stage programs. Each product in our pipeline has potential for additional indications beyond their initial target indications, and with this, we can save more lives and hope may become reality for even more people. YSC cookie is set by Youtube and is used to track the views of embedded videos on Youtube pages. Log In. Shareholders in NRx Pharmaceuticals (NASDAQ: NRXP) have seen a 60% decline today. We boldly address the life-threatening diseases facing the world today that often go untreated - by researching, developing, and scaling solutions to help people who most desperately need them. These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc. Cautionary Note Regarding Forward-Looking Statements. This cookie is used for counting the new visitors to the website by assigning a unique visitor ID. NRx Pharmaceuticals announces that the US Food and Drug Administration (FDA) has declined to issue an Emergency Use Authorization (EUA) for ZYESAMI (aviptadil). This cookie is set by GDPR Cookie Consent plugin. Learn more about our clinical trial for severe bipolar depression with Sub-Acute Suicidal Ideation & Behavior (SSIB). NRx Pharmaceuticals Raises $25M Via Equity To Support Its Pipeline Development Main Markets News Today Credit Suisse Slashes Global Equities Call, Warns of More Pain Ahead One of the tragic results of the pandemic years is the deteriorating mental health of many Americans a vicious trend that has spared no one. This cookie is set by Rubicon Project to control synchronization of user identification and exchange of user data between various ad services. Towards innovative clinical protocols requests by a client are sent to the same origin server of bipolar Nrx-101 is not currently available outside of clinical trials certify that you are a Healthcare by. 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